For some issues, functional type I allergy tests have proved to be a useful complement to the detection of IgE antibodies In the basophil degranulation test (BDT), basophil granulocytes from the patient's blood are concentrated and stimulated in the laboratory with allergen extracts or native food (which is sent in also).
The BDT is a complement to the IgE testing in the case of the following issues:
Detection of specific IgE (CAP testing):
10 ml whole blood is sufficient for a minimum of 20 allergens.
Food IgE blot (20 allergens): 10 ml whole blood
Basophil degranulation test (BDT): 2 ml EDTA blood, or alternatively, heparin blood per allergen